_Antoine LORRAINE ________________+
                                                             | (1489 - 1544)                    
                                _Francis I LORRAINE _________|
                               | (1517 - 1545) m 1541        |
                               |                             |_Renée of BOURBON-MONTPENSIER ___+
                               |                               (1494 - 1539)                    
 _Charles III LORRAINE ________|
| (1542 - 1608)                |
|                              |                              _Christian II OLDENBURG __________+
|                              |                             | (1481 - 1558) m 1514             
|                              |_Christina of OLDENBURG _____|
|                                (1521 - 1590) m 1541        |
|                                                            |_Isabella of HABSBURG ____________+
|                                                              (1501 - 1525) m 1514             
|
|--Anne of LORRAINE 
|  (1569 - 1576)
|                                                             _Francis I VALOIS-ANGOULÊME _____+
|                                                            | (1494 - 1547) m 1514             
|                               _Henry II VALOIS-ANGOULÊME _|
|                              | (1519 - 1559)               |
|                              |                             |_Claude of VALOIS-ORLÉANS _______+
|                              |                               (1499 - 1524) m 1514             
|_Claude of VALOIS-ANGOULÊME _|
  (1547 - 1574)                |
                               |                              _Lorenzo de' MEDICI ______________+
                               |                             | (1492 - 1519)                    
                               |_Catherine de' MEDICI _______|
                                 (1519 - 1588)               |
                                                             |_Madeleine of LA TOUR-D'AUVERGNE _
                                                               (1498 - 1519)