_Philip I HABSBURG _______+
                                                  | (1478 - 1506)            
                          _Charles V HABSBURG ____|
                         | (1499 - 1558) m 1526   |
                         |                        |_Joanna I of TRASTÁMARA _+
                         |                          (1479 - 1555)            
 _Philip II HABSBURG ____|
| (1527 - 1598) m 1543   |
|                        |                         _Manuel I AVIZ ___________+
|                        |                        | (1469 - 1521)            
|                        |_Isabella of AVIZ ______|
|                          (1503 - 1539) m 1526   |
|                                                 |_Maria of TRASTÁMARA ____+
|                                                   (1482 - 1516)            
|
|--Carlos HABSBURG 
|  (1545 - 1568)
|                                                  _Manuel I AVIZ ___________+
|                                                 | (1469 - 1521)            
|                         _John III AVIZ _________|
|                        | (1502 - 1557)          |
|                        |                        |_Maria of TRASTÁMARA ____+
|                        |                          (1482 - 1516)            
|_Maria Manuela of AVIZ _|
  (1527 - 1545) m 1543   |
                         |                         _Philip I HABSBURG _______+
                         |                        | (1478 - 1506)            
                         |_Catherine of HABSBURG _|
                           (1506 - 1577)          |
                                                  |_Joanna I of TRASTÁMARA _+
                                                    (1479 - 1555)