_Rene GUISE ___________+
                                                          | (1536 - 1566) m 1554  
                                   _Charles I GUISE ______|
                                  | (1556 - 1605) m 1582  |
                                  |                       |_Louise of RIEUX ______
                                  |                         (1531 - 1570) m 1554  
 _Charles II GUISE _______________|
| (1596 - 1657) m 1619            |
|                                 |                        _______________________
|                                 |                       |                       
|                                 |_Marguerite of CHABOT _|
|                                   (1565 - 1652) m 1582  |
|                                                         |_______________________
|                                                                                 
|
|--François Louis GUISE 
|  
|                                                          _Antoine BOURBON ______+
|                                                         | (1518 - 1562)         
|                                  _Henry IV BOURBON _____|
|                                 | (1553 - 1610)         |
|                                 |                       |_Jeanne III of ALBRET _+
|                                 |                         (1528 - 1572)         
|_Catherine Henriette of BOURBON _|
  (1596 - 1663) m 1619            |
                                  |                        _______________________
                                  |                       |                       
                                  |_Gabrielle of ESTREES _|
                                    (1573 - 1599)         |
                                                          |_______________________