A Family Genealogy of
the Gentle House of Stapleton
the Gentle House of Stapleton
Augustus Frederick ESTE #71328
13 JAN 1794 - 28 DEC 1848
Personal Information
- BIRTH: 13 JAN 1794, London, England
- DEATH: 28 DEC 1848, Ramsgate, Kent, England
Notes
Augustus d'Este is the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made.[3][4][5] The course of his MS, which was not diagnosed during his lifetime, is known from the diaries he kept. D'Este left a detailed diary describing his 22 years living with the disease. He began his diary in 1822 and it had its last entry in 1846; only to remain unknown until 1948.[6] His symptoms began at age 28, with a sudden transient visual loss after the funeral of a friend. During the course of his disease he developed weakness of the legs, clumsiness of the hands, numbness, dizziness, bladder disturbances, and erectile dysfunction. By 1843 he was experiencing persistent symptoms including tremor and nocturnal spasms, and in 1844 he began to use a wheelchair. In his last years he was confined to his bed. Despite his illness, he kept an optimistic view of life.
Parents
Father: Augustus Frederick HANOVER #71308
Mother: Augusta MURRAY #71327
_Frederick Louis HANOVER _________+
| (1706 - 1751)
_George III William HANOVER ____________|
| (1738 - 1820) m 1761 |
| |_Augusta of SAXE-GOTHA-ALTENBURG _+
| (1719 - 1772)
_Augustus Frederick HANOVER _|
| (1773 - 1843) m 1793 |
| | __________________________________
| | |
| |_Sophia Charlotte MECKLENBURG-STRELITZ _|
| (1744 - 1818) m 1761 |
| |__________________________________
|
|
|--Augustus Frederick ESTE
| (1794 - 1848)
| __________________________________
| |
| ________________________________________|
| | |
| | |__________________________________
| |
|_Augusta MURRAY _____________|
(1761 - 1830) m 1793 |
| __________________________________
| |
|________________________________________|
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|__________________________________