______________________
                                                  |                      
                        _Constantine ANGELOS _____|
                       | (1093 - 1166)            |
                       |                          |______________________
                       |                                                 
 _John KOMNENOSDOUKAS _|
| (1125 - 1200)        |
|                      |                           _Alexios I KOMNENOS __+
|                      |                          | (1057 - 1118)        
|                      |_Theodora of KOMNENOS ____|
|                        (1095 - ....)            |
|                                                 |_Irene of DOUKAS _____+
|                                                   (1066 - 1137)        
|
|--Manuel KOMNENOSDOUKAS 
|  (1186 - 1241)
|                                                  ______________________
|                                                 |                      
|                       _Constantine MAKRODOUKAS _|
|                      | (.... - 1185) m 1166     |
|                      |                          |______________________
|                      |                                                 
|_Zoe of MAKRODOUKAS __|
                       |
                       |                           _Isaac KOMNENOS ______+
                       |                          | (1113 - 1160)        
                       |_Anna of KOMNENOS ________|
                         (1135 - ....) m 1166     |
                                                  |_Theodora of UNKNOWN _
                                                    (.... - 1142)