_Rene II LORRAINE ______+
                                                            | (1451 - 1508)          
                              _Antoine LORRAINE ____________|
                             | (1489 - 1544)                |
                             |                              |_Philippa of EGMOND ____+
                             |                                (1462 - 1546)          
 _Nicholas LORRAINE _________|
| (1524 - 1576) m 1569       |
|                            |                               ________________________
|                            |                              |                        
|                            |_Rene of BOURBON-MONTPENSIER _|
|                              (1494 - 1539)                |
|                                                           |________________________
|                                                                                    
|
|--Antoine LORRAINE 
|  (1572 - 1587)
|                                                            _Claude LORRAINE _______+
|                                                           | (1496 - 1550) m 1513   
|                             _Claude GUISE ________________|
|                            | (1526 - 1572)                |
|                            |                              |_Antoinette of BOURBON _+
|                            |                                (1494 - 1582) m 1513   
|_Catherine Romula of GUISE _|
  (1550 - 1606) m 1569       |
                             |                               ________________________
                             |                              |                        
                             |_Louise of BRÉZÉ ___________|
                               (.... - 1576)                |
                                                            |________________________