_Claude LORRAINE __________+ | (1496 - 1550) m 1513 _Francis II GUISE ___| | (1518 - 1562) m 1548| | |_Antoinette of BOURBON ____+ | (1494 - 1582) m 1513 _Henry I GUISE _________| | (1550 - 1588) m 1570 | | | _Ercole II ESTE ___________ | | | (1508 - 1559) | |_Anna of ESTE _______| | (1531 - 1607) m 1548| | |_Renee of VALOIS-ORLÉANS _+ | (1510 - 1574) | |--Marie of GUISE | (1577 - 1582) | ___________________________ | | | _____________________| | | | | | |___________________________ | | |_Catherine of LA MARCK _| (1548 - 1633) m 1570 | | ___________________________ | | |_____________________| | |___________________________