_Francis I LORRAINE _________+
| (1517 - 1545) m 1541
_Charles III LORRAINE ________|
| (1542 - 1608) |
| |_Christina of OLDENBURG _____+
| (1521 - 1590) m 1541
_Henry II LORRAINE _____|
| (1563 - 1624) |
| | _Henry II VALOIS-ANGOULÊME _+
| | | (1519 - 1559)
| |_Claude of VALOIS-ANGOULÊME _|
| (1547 - 1574) |
| |_Catherine de' MEDICI _______+
| (1519 - 1588)
|
|--Nicole of LORRAINE
| (1608 - 1656)
| _Guglielmo GONZAGA __________+
| | (1538 - 1587)
| _Vincenzo I GONZAGA __________|
| | (1562 - 1611) |
| | |_Eleanor of HABSBURG ________+
| | (1534 - 1594)
|_Margherita of GONZAGA _|
(1591 - 1631) |
| _Francesco I de' MEDICI _____+
| | (1541 - 1587)
|_Eleanor de' MEDICI __________|
(1566 - 1611) |
|_Joanna of HABSBURG _________+
(1546 - 1578)