_Girolamo ORSINI ______+
                                                    |                       
                       _Paolo Giordano ORSINI ______|
                      | (1541 - 1585) m 1558        |
                      |                             |_Francesca of SFORZA __
                      |                                                     
 _Virginio ORSINI ____|
| (1572 - 1615) m 1589|
|                     |                              _Cosimo I de' MEDICI __+
|                     |                             | (1519 - 1574)         
|                     |_Isabella Romola de' MEDICI _|
|                       (1542 - 1576) m 1558        |
|                                                   |_Eleanor Alvarez ALBA _+
|                                                     (1521 - 1562)         
|
|--Isabella of ORSINI 
|  (1597 - 1623)
|                                                    _______________________
|                                                   |                       
|                      _____________________________|
|                     |                             |
|                     |                             |_______________________
|                     |                                                     
|_Flavia DAMASCENI ___|
  (1574 - 1606) m 1589|
                      |                              _______________________
                      |                             |                       
                      |_____________________________|
                                                    |
                                                    |_______________________