Hawise Lestrange was the daughter of the Marcher lord John Lestrange (d.1269) of Great Ness, Cheswardine and Knockin (Shropshire). Married at a young age to the ruler of southern Powys, Gruffudd ap Gwenwynwyn, she became a key figure in border affairs and in the management of her family and estates until her death at a great age. She was deeply implicated in a plot to overthrow the prince of Wales, Llywelyn ap Gruffudd, in 1274, and with her husband sided with Edward I in the English king's conquest of Wales.